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Eiffel Tower - Wikipedia. The Eiffel Tower (EYE- f. It is named after the engineer Gustave Eiffel, whose company designed and built the tower. Constructed from 1. World's Fair, it was initially criticized by some of France's leading artists and intellectuals for its design, but it has become a global cultural icon of France and one of the most recognisable structures in the world. Its base is square, measuring 1. During its construction, the Eiffel Tower surpassed the Washington Monument to become the tallest man- made structure in the world, a title it held for 4. Chrysler Building in New York City was finished in 1. Due to the addition of a broadcasting aerial at the top of the tower in 1. Chrysler Building by 5. Excluding transmitters, the Eiffel Tower is the second- tallest structure in France after the Millau Viaduct. The tower has three levels for visitors, with restaurants on the first and second levels. The top level's upper platform is 2. European Union. Tickets can be purchased to ascend by stairs or lift (elevator) to the first and second levels. The climb from ground level to the first level is over 3. Although there is a staircase to the top level, it is usually accessible only by lift. History. Origin. The design of the Eiffel Tower was the product of Maurice Koechlin and . Eiffel openly acknowledged that inspiration for a tower came from the Latting Observatory built in New York City in 1. Sauvestre added decorative arches to the base of the tower, a glass pavilion to the first level, and other embellishments. The new version gained Eiffel's support: he bought the rights to the patent on the design which Koechlin, Nougier, and Sauvestre had taken out, and the design was exhibited at the Exhibition of Decorative Arts in the autumn of 1. On 3. 0 March 1. 88. Eiffel presented his plans to the Soci. A budget for the exposition was passed and, on 1 May, Lockroy announced an alteration to the terms of the open competition being held for a centrepiece to the exposition, which effectively made the selection of Eiffel's design a foregone conclusion, as entries had to include a study for a 3. Champ de Mars. On 1. May, a commission was set up to examine Eiffel's scheme and its rivals, which, a month later, decided that all the proposals except Eiffel's were either impractical or lacking in details. After some debate about the exact location of the tower, a contract was signed on 8 January 1. This was signed by Eiffel acting in his own capacity rather than as the representative of his company, and granted him 1. Eiffel was to receive all income from the commercial exploitation of the tower during the exhibition and for the next 2. He later established a separate company to manage the tower, putting up half the necessary capital himself. These objections were an expression of a long- standing debate in France about the relationship between architecture and engineering. It came to a head as work began at the Champ de Mars: a . A petition called . And for twenty years . Will it not also be grandiose in its way? And why would something admirable in Egypt become hideous and ridiculous in Paris? Eiffel was similarly unworried, pointing out to a journalist that it was premature to judge the effect of the tower solely on the basis of the drawings, that the Champ de Mars was distant enough from the monuments mentioned in the protest for there to be little risk of the tower overwhelming them, and putting the aesthetic argument for the tower: . The west and north legs, being closer to the river Seine, were more complicated: each slab needed two piles installed by using compressed- air caissons 1. Each of these slabs supported a block of limestone with an inclined top to bear a supporting shoe for the ironwork. Each shoe was anchored to the stonework by a pair of bolts 1. The foundations were completed on 3. June, and the erection of the ironwork began. The visible work on- site was complemented by the enormous amount of exacting preparatory work that took place behind the scenes: the drawing office produced 1,7. The finished components, some already riveted together into sub- assemblies, arrived on horse- drawn carts from a factory in the nearby Parisian suburb of Levallois- Perret and were first bolted together, with the bolts being replaced with rivets as construction progressed. No drilling or shaping was done on site: if any part did not fit, it was sent back to the factory for alteration. In all, 1. 8,0. 38 pieces were joined together using 2. This renewed concerns about the structural integrity of the tower, and sensational headlines such as . They made use of the guides for the lifts which were to be fitted in the four legs. The critical stage of joining the legs at the first level was completed by the end of March 1. Although construction involved 3. Note the drive sprockets and chain in the foreground. Equipping the tower with adequate and safe passenger lifts was a major concern of the government commission overseeing the Exposition. Although some visitors could be expected to climb to the first level, or even the second, lifts clearly had to be the main means of ascent. Lead weights on some links of the upper or return sections of the chains counterbalanced most of the car's weight. The car was pushed up from below, not pulled up from above: to prevent the chain buckling, it was enclosed in a conduit. At the bottom of the run, the chains passed around 3. Smaller sprockets at the top guided the chains. No French company wanted to undertake the work. The European branch of Otis Brothers & Company submitted a proposal but this was rejected: the fair's charter ruled out the use of any foreign material in the construction of the tower. The deadline for bids was extended but still no French companies put themselves forward, and eventually the contract was given to Otis in July 1. Motive power was provided by an inclined hydraulic ram 1. Five fixed sheaves were mounted higher up the leg, producing an arrangement similar to a block and tackle but acting in reverse, multiplying the stroke of the piston rather than the force generated. The hydraulic pressure in the driving cylinder was produced by a large open reservoir on the second level. After being exhausted from the cylinder, the water was pumped back up to the reservoir by two pumps in the machinery room at the base of the south leg. This reservoir also provided power to the lifts to the first level. The original lifts for the journey between the second and third levels were supplied by L. A pair of 8. 1 m (2. One lift car was mounted on top of these rams: cables ran from the top of this car up to sheaves on the third level and back down to a second car. Each car only travelled half the distance between the second and third levels and passengers were required to change lifts halfway by means of a short gangway. The 1. 0- ton cars each held 6. Most of the party chose to stop at the lower levels, but a few, including the structural engineer, . At 2: 3. 5 pm, Eiffel hoisted a large Tricolour to the accompaniment of a 2. The tower was an instant success with the public, and nearly 3. May. Two searchlights mounted on a circular rail were used to illuminate various buildings of the exposition. The daily opening and closing of the exposition were announced by a cannon at the top. There was also a p. Graffitists were also catered for: sheets of paper were mounted on the walls each day for visitors to record their impressions of the tower. Gustave Eiffel described some of the responses as vraiment curieuse (. It was to be dismantled in 1. City of Paris. The City had planned to tear it down (part of the original contest rules for designing a tower was that it should be easy to dismantle) but as the tower proved to be valuable for communication purposes, it was allowed to remain after the expiry of the permit. Adobe Flash PlayerAdobe Shockwave Player. Providing enriching experiences to over 4. Over 4. 50 million Internet- enabled desktops have Adobe Shockwave Player installed. These users have access to some of the best content the Web has to offer - including dazzling 3. D games and entertainment, interactive product demonstrations, and online learning applications. Chrome Flash Player Download FreeAdobe Flash Player, free and safe download. 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Process name: Services and Controller app. Product: Windows. Company: Microsoft. To locate your Windows Registry files you will need to know which Windows platform you have. There are currently only two Windows platforms that all versions of. Kennedy Software - Running Old Apps under W2K/NT/XP. If you have any questions about why I disable a certain service, feel free to ask. Instead, use the following four lines: MD TEMP COPY C:\WINDOWS\SYSTEM32\CONFIG\SYSTEM C:\WINDOWS\TEMP\SYSTEM.BAK. How to fix csrss.exe related problems? Run Security Task Manager to check your csrss process 2. Run Windows Repair Tool to repair csrss.exe related Windows Errors. Is the problem specific to a certain guest OS? Specific release of a guest OS? Especially with Linux guest related problems, the issue may be. Cannot Copy Windows System32 Config Software PiracyFile: services. exe. Security Rating: This is the Services Control Manager, which is responsible for running, ending, and interacting with system services. Use this program to start services, stop them, or change their default from automatic to manual startup. In other cases, services. Read also the 2. 73 reviews. Tanveer Windows Service Manger Walle if it is in the directory c: \windows\lsass directory it is dangerous hiarto miarto winlogon Services. See also: Link. Martin Should it be blocked by my firewall? C: \Windows\System. If its a trojan and you can't remove check text in file for other potential trojan files. Nautis c: \windows\services. Blocked with zone alarm, but still cant get rid of it. Some other process must be restoring the file at start up. Any ideas anyone? Myke It is some kind trojan, it takes control of systems, rpc- overflow. The Windows 2. 00. B. Some other application (possibly C: \WINNT\jave. I deleted it. John My firewall asks if I want to allow it. If I do not, my AOL will not access the web except for e- mail. Herb. 30 should be in windows/system. S. exe is OK! Try deleting it with Security Task Manager then delete the directory and the entries in the registry : HKEY. Jose The services. I renamed services. Afterwards I cleaned the registry manually Henrik It's the My. Doom virus if found in c: \Windows wolud try to connect tcp 2. Roland Backdoor. Zincite. A uses this file. The file is also referred to in registry to run at startup. Pieter Rabie c: \windows\system. Follow the link for the registry fix and delete both C: Windows/services. C: Windows/System. I did and it's no longer on my computer and trying to dial out See also: Link. Jake trojan dropper (downloaded onto my computer from a porn site to path: C: \windows\system. Microsoft has issues and spying on Customers is one of them .. Services & Controller App Received it from an msn- user, after giving him my IP- adress (stupid!!), as . Became Services. exe after starting server. Clever bastards. Thomas read this! I haven't installed office at all, nor would it ever be there.. Nick It came up as a trojan on AVG, I deleted the little sod. Norton detects it on a virus scan, but I can't delete it. Should I be worried? Why keep it, you don't need it! Just delete it! Qinglin Is present in C: \WINDOWS\system. C: \WINDOWS\$Nt. Service. Pack. Uninstall$ (1. C: \WINDOWS\Service. Pack. Files\i. 38. Shane Well if you don't need to run your system go ahead and delete it. I would leave it be though. From what I understand services. In the olden days when we would stop services remotely as a joke it would bluescreen the victims computer. I think ms fixed it so you can no longer stop it. John Kline It's safe if it's in the System. However, I've come across it in this folder before, meaning it's not legit: C: \WINDOWS\SYSTEM\windows\services. Kevin Gallo Consumes ~8. NT/win. 20. 00/XP,and it doesn't let u to delete dis file, i haven't experienced that file,but experienced a similar file to services. My friend said that this file is both in windows\system. But if u open that services. VB,C++) and remove the entire codes,lines,etc.. I mean it shall be an empty file,erase everything within,and save changes,and also prevent this file to run itself during reboot as in registry. Thus u will get rid of that file dread knight May be related to the Coolsearch adware, I've got a services. C: \Windows\System. MSOffice and another in C: \Windows\System. MSOffice is created on the same date I detect the adware. Kang windows\inetdim\services. Then I deleted the inetdim directory and no more issues cuerx INETDIM= dangerous!!!!! Cannot execute any setup. Cheers Andy Running as an unprivileged user I have no problems with this process, but when I log on as Administrator the services. CPU (according to MS's Task Manager). The only file Find turns up with this name is in the right directory, so presumably legitimate. I have no idea what is going on; can anyone advise? Just Infected Virus has 2 files: c: \windows\services. Virus is a keylogger that sends an e- mail with your keystroken everytime you connect Internet; blocks Windows XP SP2 protect shield and the Windows Xp . You must erase the 2 files and then clean the register. Binefa Palou Its a file that is part of Windows, any file that you see, with weird names, check in System 3. Reguardless, I suggest having NORTON 2. Scan your computer every three days, and dont be surfing those porn sites as much and you wont have as many Viruses! Ryan Critchett Trojan Stephen after a combined trojan attack, i had a file in system. HJT and Find It! Since in Properties dialog it didn't have any mention of Microsoft, i deleted it in safe mode, with no bad effects. Karo service. exe (not services. Once it has loaded as a process it is deleted from the windows system folder. I have yet to locate it because of this. How ever some viruses call it to perform malicious acts. Search your registry in the (HKEY. Once it was recognized by ZA if I deny it access I have NO internet access whatsoever. Path is C: \WINNT\System. I see alot of conflicting info here but I want it off, any suggestions? I'm a novice.. Bob When I do a search, it comes up in the System. C\: windows\System. Is the file in the dllcache ok or is it a virus? Bob H My system was sending and receiving without my request. I read these notes, deleted c: \windows\system\services. Jon The real deal (for win 2k): C: \WINNT\system. AND- C: \WINNT\Service. Pack. Files\i. 38. Windows Operating System services and manages the operation of starting and stopping services like net connection. DO NOT REMOVE THESE FILES. To COMPLETELY remove them you'll need to find what other files are reinstating them. The free downloadable Hi. Jack. This . Next powerdown and at startup press F8 (safemode) to remove the associated files. Jesper Normally an system process (in windows- folder) Zutty It has a keylogger and sends an e- mail with your keystroken everytime you connect Internet. It is associed with the file . Billy my cpu is 1. It runs alongside the microsoft services. C: \windows\system. Nothing detects it as a virus/adware/trojan etc and when i delete it it apears again after reboot. Have found refrences within the file to www. Only 1. 1Kb in size. I have no fix yet.. Browne. R If located in c: \windows and is about 1. C: \windows\system. Browne. R 6. 5 kb cant shut it down , located in windows/inet. Win- User I understand in itself, it's not a bad file BUT it CAN be dangerous. I notice that when I stop all the rundll. I always have like 1. I STOP getting pop- ups. The minute a pop- up window comes to annoy me, I check the programs running in task manager and what do you know! Rundll. 32. exe is BACK! I did the experiment a few times so there IS a link between that process and stupid pop- ups, the question is, HOW do I go the root of that process and delete what needs to be deleted? Melissa is also in a service pack, swallows much CPU during boot Flyervv CPU Utilization in Services. Increases to 1. 00 Percent for 3 minutes every time i connect to the web. Ronen I suspect this file is using my computer to mail unwanted eml to some targeted port. I had over 1. 20 messages scanned by avg that weren't even in my mailbox. I went to task to see what was using so much rescources and found this services. I next did a file search and found it in system 3. I wasn't sure about which one was legitimate, so I came to this page. Don't start deleting things until you are certain that the file is malicious. Jerry The application or DLL C: \WINDOWS\system. Please check this against your installation diskette. Losing my mind~ I found a duplicate of services. It said that it had been created earlier in the week. I just renamed the little bugger to an inert file type. Traffic Generator FreeThese tools will either generate traffic and transmit it, retransmit traffic from a capture file, perhaps with changes. Ostinato Network Traffic Generator. Windows ! Please read the HOWTO- INSTALL. Buy dmg ($2+)Older versions are also available - some for free. Thanks to @atulchitnis (RIP) for his help in finding and @gkjohn for lending his Mac Mini to revive Ostinato development/support on OSX. Python APISee Python Scripting for installation and usage instructions. Buy python- ostinato ($1. Older versions are available at Py. Pi. BSDOstinato is available in the Free. BSD ports and packages collection. To install the pre- compiled binary package - $ pkg install ostinato. Alternatively, you can build and install the port - $ cd /usr/ports/net/ostinato/. Drone Appliance. This VM appliance contains just the drone server which is auto- started at boot. The Internet is positively riddled with traffic generators. They range from low-quality autorefresh bots using proxies to appear as though they come from around the. Never buy targeted web site traffic if you can get it free using website traffic software. Viral Web site Traffic in Minutes. Ostinato Network Traffic Generator - Software downloads and install instructions - Windows, Linux, Mac OSX, BSD. Virtual Appliance VMs. Live CD/USB. Traffic Generator is a tool that allows to evaluate performance of DUT (Device Under Test) or SUT (System Under Test). Tool can generate and send RAW packets. The appliance is distributed in ovf/ova format which is supported by all the popular hypervisors including KVM, VMware and Virtual. Box. Run the Ostinato client on any PC/Mac desktop and connect to the appliance. Download the images from SUSE Gallery (you may need to create an account or use an existing Open. ID). Community member Bernhard has created a custom v. Drone appliance for use with GNS3 based on Tiny. Core Linux - see Ostinato for GNS3 for download and detailed usage instructions. Live CD/USBConverts any PC to a dedicated traffic generator by using the Live CD/USB. Because there is only a minimal OS and there are no competing applications for CPU and memory, running Ostinato as a Live CD/USB will achieve higher traffic rates than running the Ostinato application in a traditional OS. Note: This distribution includes both the Ostinato client and Drone server and runs a Linux Kernel with minimal X and a bare- bones window manager. Download the images from SUSE Gallery (you may need to create an account or use an existing Open. ID). Source. See Building from Source for build instructions for your platform. Download (src)Older versions are also available.
Proteomics has emerged as an indispensable methodology for large-scale protein analysis in functional genomics. The Escherichia coli proteome has been extensively. 4 Oncoproteomics for Personalized Management of Cancer K. Jain CONTENTS 1 Introduction 2 Role of Proteomics in Discovery of Biomarkers of Cancer 3 Application of. Past, Present, and Future Prospects. The recent studies on the E. An enormous number of E. Previously, one or more proteins were chosen as models for understanding local physiological phenomena. These days, proteomic studies allow researchers to identify large members of stimulons or regulons and to obtain information that indicates which specific proteins should be studied further. When subjected to environmental perturbations, E. Up- and downregulation of specific protein sets is seen in response to a number of chemical and physical stresses, such as heat, oxidative agents, and hyperosmotic shock; these responses are thought to act as protective mechanisms leading to elimination of the stress agent and/or repair of cellular damage. Thus, the cellular responses, as reflected by the proteome, can differ widely according to the stresses imposed. Comparative proteome profiling under various genotypic and environmental conditions can reveal new regulatory circuits and the relative abundances of protein sets at the system- wide level. In one of the first studies using proteomics, comparison of 2- D gels allowed identification of a large group of E. In the following years, many E. These studies resulted in the identification of various E. The applied stresses were found to affect the observable proteome size by anywhere from a few proteins to nearly half of the proteins in the cell. Some of the altered proteins appear to be general stress- induced proteins, while others appear specific to particular environmental stimuli. More importantly, these studies also showed that the responses of an organism to an environmental stimulus are not simply the sum of independent responses of individual genes but rather seem to be a coordinated series of linked events leading to cross- adaptation among the stress responses. The cascade- like regulation observed with various stimulons and/or regulons in a complex regulatory network. The circles indicate regulons, while the rectangles indicate stimulons. Stimulons in which proteins are induced by stimuli such as stationary.. The complex and physiologically far- reaching responses of E. These master regulators, which serve as the decisive information- processing units, connect complex signaling networks with the downstream regulatory cascades or networks that ultimately control expression of the response- associated genes. A regulon is a set of proteins whose synthesis is regulated by the same regulatory proteins, while a stimulon is a set of proteins whose amount or synthesis rate changes in response to a certain stimulus. At the molecular level, each stimulon may be composed of more than one regulon, each controlled by a different molecular factor. The dissection of stimulons into regulons is based on comparison of the induction patterns in wild- type cells versus those of strains having mutations in known regulatory elements. In this way, regulators such as the RNA polymerase sigma factor Rpo. S (1. 92), the histone- like protein H- NS (1. Lrp (6. 1) have been studied based on the comparative analysis of wild- type and mutant or double mutant strains. The highly complex and nonlinear behaviors of these networks have complicated their studies, but proteomic analysis of cells stimulated by one or more signals (stimulons) or cells lacking one or more global regulators (regulons) has provided new insight into the stimulus- response processes in E. Proteomics has allowed researchers to isolate new stress- associated and stress- specific protein markers, identify all proteins controlled by a certain regulatory protein, and understand the integrated cellular metabolic and regulatory networks. Here, several main cellular responses of E. Moreover, a main regulator and/or its coordinated regulators in response to each stress are discussed. Stationary- phase response. At the onset of the stationary phase, E. Overall, these properties result in better cell survival under adverse conditions. One top- level master regulator of this genetic program is an RNA polymerase sigma factor called Rpo. S (. These genes were identified by transcriptional analysis of specific genes as well as by proteomic approaches (Fig. As shown in Fig. Additionally, these genes are regulated by transcription factors specific for certain stress responses (e. Oxy. R, which is involved in the oxidative stress response) or more- global regulators, such as H- NS, IHF, cyclic AMP (c. AMP)- c. AMP receptor protein (CRP), and Lrp (1. These regulators can individually or coordinately affect many . For instance, comparative proteome analysis of an H- NS deletion mutant and the wild- type strain revealed that some of the . Dps was rapidly degraded during exponential growth by the protease Clp. XP (which is regulated by . This, along with increased Dps synthesis, results in the high- level accumulation of Dps during the stationary phase (2. Dps levels are specifically controlled under certain stress conditions. In addition, studies have shown that . Collectively, these findings indicate that . Protein expression in E. This response plays a critical role in protecting the cells from temperature stress, producing tolerance, or repairing cellular systems. Similarly, a separate, nonoverlapping group of proteins known as cold shock proteins are produced during the period of growth cessation following a shift from 3. Some of the other heat shock proteins are proteases that function to degrade misfolded or abnormal proteins (2. These proteins were first recognized as being highly abundant when examined with 2- D gels in 1. Later, Neidhardt and colleagues (2. D gels to monitor the synthesis rates of individual proteins before and after heat shock and identified a number of proteins whose synthesis rates were dramatically increased following the temperature increase. Initially, these proteins were named by their positions on 2- D gels. Later, many of the spots were identified as known gene products, including Dna. K (7. 7), Gro. EL (2. Gro. ES (2. 84), Grp. E (3. 35), La (lon) protease (2. Lys. U (1. 68). The characterized proteins include the main cellular chaperones, Dna. K and Gro. ELS; the ATP- dependent proteases Clp. P, Deg. P, Fts. H (Fhl. B), Hsl. VU, and La; and other proteins involved in protein folding, refolding, quality control, and degradation (2. Other important heat shock proteins include HTS (homoserine transsuccinylase), which is a key enzyme in methionine biosynthesis (2. Htr. M (2. 40) and Ppi. D (5. 5); and the vegetative sigma factor . In addition, E. It is thus possible that the heat- mediated induction of some genes may occur via other mechanisms and regulators that remain to be elucidated. For example, members of the phage shock protein (Psp) family, which are induced in response to filamentous phage infection as well as in response to heat, ethanol, and osmotic shock, do not require the action of . Furthermore, a large set of heat shock proteins was found to be induced by other stimuli, such as exposure to denaturing conditions (i. The proteins induced under various stress conditions can overlap with one another to degrees ranging from complete overlap to no overlap at all. For example, in E. For example, proteins damaged or unfolded by elevated temperatures during heat shock tend to aggregate (1. This study is also important for the elucidation of cellular protein quality control mechanisms, because damaged proteins can be refolded with the aid of chaperones or can be degraded by proteases (8. An example of one such study is the investigation of E. Another proteomic study on the Dna. KJ- and ribosome- associated trigger factor mutant strains revealed approximately 3. All major aggregated proteins were shared between the two mutants, indicating that they cooperatively assist the folding of newly synthesized proteins in E. |
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